Shire plc, a leading global biotechnology company focused on rare diseases announces today that it has entered into a definitive agreement with Servier to sell its Oncology business for $2.4 billion. Shire’s Oncology business includes in-market products ONCASPAR® (pegaspargase), a component of multi-agent treatment for acute lymphoblastic leukemia (ALL) and ex-U.S. rights to ONIVYDE® (irinotecan